I think you could get some more useful advise if you posted your current setup and also what you plan on doing (why your upgrading).
My video card died recently and I had to revert back to my older SLI setup - but since all they really apply to (for me lately) is playing E&B, they made absolutely no difference. I'm going to wait till I need to upgrade to buy newer tech.
PS - I agree on the RAM, I've yet to use all 4G of mine.