Haven't seen this mentioned.
Usually happens after ALT-TABing in and out. all the left mouse click functions don't seem to work. It is somewhat random, can be checking email, chatting in yahoo, viewing a web page ect.
Come back into the game and click to loot a roid, try to click on a warp point, click warp, click to enter a base/land on planet or gate and it doesn't register the click.
Just wanting to know if anyone else has had this happen and/or if there is a fix for it.